Treatment of severe dialysis reactions with the AN69-ST membrane: biocompatibility does matter

Treatment of severe dialysis reactions with the AN69-ST membrane: biocompatibility does matter

Dialysis reactions with biocompatible membranes are rare, and complement activation has been suggested to be a culprit. We report here a case of an incident haemodialysis patient with asthma disease who experienced severe adverse reactions late into dialysis session, with different synthetic membranes (FX 80, Fresenius; Polyflux 17L, Gambro; FX 10, Fresenius; BLS 512, Bellco-Sorin). After repla...

ACE inhibitors and anaphylactoid reactions to high-flux membrane dialysis (AN69): clinical aspects.

Dialysis Efficiency of AN69, a Semisynthetic Membrane Not Well Suited for Diffusion

AN69 membrane is not suited for diffusion, with an suggested limit at 25 mL/min dialysate flow rate. When prescribing continuous hemodialysis this threshold must be surpassed to achieve. We designed a study aimed to check if a higher dose of dialysis could be delivered efficiently with this membrane. Ten ICU patients under continuous hemodiafiltration with 1.4 m(2) AN69 membrane were included a...

Effect of dialysis membrane biocompatibility on polymorphonuclear granulocyte activity in dialysis patients.

BACKGROUND Among patients with defects of the phagocytic component of the immune system, chronic haemodialysis patients are highly susceptible to microbial infections characterized by high morbidity/mortality, related to an impairment of the phagocytic response. Therefore the potential influence of dialysis membrane biocompatibility on the activity of polymorphonuclear (PMN) granulocytes from d...

Evaluation of the Biocompatibility of Dialysis Membranes.

BACKGROUND Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood-membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. SUMMARY The focus of investigation into dialysi...